Drugs that deplete vitamins

When taken regularly, some frequently prescribed medications can diminish or deplete your body's stores of important vitamins, minerals, and other nutrients.

If you take any medications, talk with a nutrition-oriented medical professional about whether you should add certain supplements to your daily regimen.


Antacids Pepcid, Tagamet, Zantac Vitamin B-12, folic acid, vitamin D, calcium, iron, zinc
Prevacid, Prilosec Vitamin B-12
Antibiotics Amoxicillin, Erythromycin, Penicillin, Tetracycline "Friendly"/beneficial intestinal bacteria
Antidepressants Adapin, Aventyl, Elavil, Tofranil Vitamin B-2, coenzyme Q-10
Antidiabetic drugs Dymelor, Micronase, Tolinase Coenzyme Q-10
Glucophage Vitamin B-12
Anti-inflammatories Aspirin Vitamin C, folic acid, iron, potassium
Advil, Aleve, Dolobid, Feldene, Indocin, Lodine, Motrin, Nalfon, Naprosyn, Orudis, Relafen, Voltaren Folic acid
Betamethasone, Budesonide, Cortisone, Dexamethasone, Hydrocortisone, Methylprednisolone, Prednisolone, Prednisone Vitamin C, vitamin D, folic acid, calcium, magnesium, potassium, selenium, zinc
Blood pressure-
lowering drugs
Apresoline Vitamin B-6, coenzyme Q-10
Bumex, Edecrin, Lasix Vitamin B-1, vitamin B-6, vitamin C, magnesium, calcium, potassium, zinc
Aquatensen, Lozol, Zaroxolyn Coenzyme Q-10, magnesium, potassium, zinc
Dyrenium Folic acid, calcium, zinc
Blocadren, Cartrol, Corguard, Inderal, Kerlone, Lopressor, Normodyne, Sectral, Tenormin, Viskin Coenzyme Q-10
lowering drugs
Baycol, Lescol, Lipitor, Mevacor, Zocor Coenzyme Q-10
Colestid, Questran Vitamin A, beta-carotene, vitamin B-12, vitamin D, vitamin E, vitamin K, folic acid, iron
Hormone replacement
therapy (HRT)
Evista, Prempro, Premarin, Estratab Vitamin B-2, vitamin B-6, vitamin B-12, folic acid, vitamin C, magnesium, zinc
Oral contraceptives Estrastep, Norinyl, Ortho-Novem, Triphasil Vitamin B-2, vitamin B-6, vitamin B-12, folic acid, vitamin C, magnesium, zinc
Tranquilizers Ormazine, Mellaril, Prolixin, Thorazine Vitamin B-2, coenzyme Q-10
Haldol Coenzyme Q-10
Source: Drug-Induced Nutrient Depletion Handbook, by R. Pelton et al.; Physician's Desk Reference

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