SADS Foundation Quarterly Literature Review

July 2005

Brugada Syndrome

 

Bernard M, Marie I, Durand A, Heron F, Levesque H.

 

Brugada syndrome.
Rev Med Interne. 2005 Jul;26(7):592-3. Epub 2004 Dec 7. French. No abstract available.
PMID: 15996572 [PubMed - in process]

 

Auerbach H, Blank R, Jank K, Gronefeld G, Klingenheben T, Marschall C, von Mengden HJ.

 

Brugada syndrome, a rare cause of syncope.
Med Klin (Munich). 2005 Jun;100(6):361-4. German.
PMID: 15968489 [PubMed - in process]

 

Bigwood B, Galler D, Amir N, Smith W.

 

Brugada syndrome following tricyclic antidepressant overdose.
Anaesth Intensive Care. 2005 Apr;33(2):266-70.
PMID: 15960413 [PubMed - in process]

 

Oe H, Takagi M, Tanaka A, Namba M, Nishibori Y, Nishida Y, Kawarabayashi T, Yoshiyama M, Nishimoto M, Tanaka K, Yoshikawa J.

 

Prevalence and Clinical Course of the Juveniles with Brugada-Type ECG in Japanese Population.
Pacing Clin Electrophysiol. 2005 Jun;28(6):549-54.
PMID: 15955188 [PubMed - in process]

 

Schulze-Bahr E, Eckardt L, Breithardt G, Seidl K, Wichter T, Wolpert C, Borggrefe M, Haverkamp W.

 

Erratum: Sodium channel gene (SCN5A) mutations in 44 index patients with brugada syndrome: Different incidences in familial and sporadic disease.
Hum Mutat. 2005 Jul;26(1):61.
PMID: 15954105 [PubMed - in process]

 

Haghjoo M, Arya A, Heidari A, Sadr-Ameli MA.

 

Suppression of electrical storm by oral quinidine in a patient with Brugada syndrome.
J Cardiovasc Electrophysiol. 2005 Jun;16(6):674. No abstract available.
PMID: 15946371 [PubMed - in process]

 

Veiser T, Laurent G, Wolf JE.

 

Brugada syndrome
Cas Lek Cesk. 2005;144(4):219-23. Czech.
PMID: 15945478 [PubMed - in process]

 

Krishna K, Lakade S, Hardas S.

 

Brugada syndrome.
Int J Cardiol. 2005 Jun 22;102(1):149-50. No abstract available.
PMID: 15939113 [PubMed - in process]

 

Shan QJ, Yang B, Chen ML, Zou JG, Xu DJ, Chen C, Li KL, Zhu PJ, Wang XB, Cao KJ.

 

The electrophysiological study and implantable cardioverter defibrillator therapy for the patients with Brugada syndrome
Zhonghua Xin Xue Guan Bing Za Zhi. 2005 Jan;33(1):34-6. Chinese.
PMID: 15924775 [PubMed - in process]

 

Meregalli PG, Wilde AA, Tan HL.

 

Pathophysiological mechanisms of Brugada syndrome: Depolarization disorder, repolarization disorder, or more?
Cardiovasc Res. 2005 May 20; [Epub ahead of print]
PMID: 15913579 [PubMed - as supplied by publisher]

 

Smits JP, Koopmann TT, Wilders R, Veldkamp MW, Opthof T, Bhuiyan ZA, Mannens MM, Balser JR, Tan HL, Bezzina CR, Wilde AA.

 

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families.
J Mol Cell Cardiol. 2005 Jun;38(6):969-81. Epub 2005 Apr 1.
PMID: 15910881 [PubMed - in process]

 

Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A.

 

Brugada syndrome: report of the second consensus conference.
Heart Rhythm. 2005 Apr;2(4):429-40. Review.
PMID: 15898165 [PubMed - indexed for MEDLINE]

 

Shimizu W, Aiba T, Antzelevitch C.

 

Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome.
Curr Pharm Des. 2005;11(12):1561-72. Review.
PMID: 15892662 [PubMed - indexed for MEDLINE]

 

Keller DI, Rougier JS, Kucera JP, Benammar N, Fressart V, Guicheney P, Madle A, Fromer M, Schlapfer J, Abriel H.

 

Brugada syndrome and fever: Genetic and molecular characterization of patients carrying SCN5A mutations.
Cardiovasc Res. 2005 May 9; [Epub ahead of print]

PMID: 15890323 [PubMed - as supplied by publisher]

 

Francis J, Antzelevitch C.

 

Brugada syndrome.
Int J Cardiol. 2005 May 25;101(2):173-8.
PMID: 15882659 [PubMed - in process]

 

Satish OS, Yeh KH, Wen MS.

 

Brugada syndrome--an update.
Chang Gung Med J. 2005 Feb;28(2):69-76. Review.
PMID: 15880981 [PubMed - indexed for MEDLINE]

 

Itoh H, Shimizu M, Takata S, Mabuchi H, Imoto K.

 

A novel missense mutation in the SCN5A gene associated with Brugada syndrome bidirectionally affecting blocking actions of antiarrhythmic drugs.
J Cardiovasc Electrophysiol. 2005 May;16(5):486-93.
PMID: 15877619 [PubMed - in process]

 

Skinner JR, Chung SK, Montgomery D, McCulley CH, Crawford J, French J, Rees MI.

 

Near-miss SIDS due to Brugada syndrome.
Arch Dis Child. 2005 May;90(5):528-9.
PMID: 15851440 [PubMed - indexed for MEDLINE]

   
   

CPVT

 

Rossenbacker T, Schollen E, Kuiperi C, de Ravel TJ, Devriendt K, Matthijs G, Collen D, Heidbuchel H, Carmeliet P.

 

Unconventional intronic splice site mutation in SCN5A associates with cardiac sodium channelopathy.
J Med Genet. 2005 May;42(5):e29.
PMID: 15863661 [PubMed - in process]

Long QT Syndrome

 

Sugao M, Fujiki A, Sakabe M, Nishida K, Tsuneda T, Iwamoto J, Mizumaki K, Inoue H.

 

New quantitative methods for evaluation of dynamic changes in QT interval using 24-hour Holter ECG recordings: QT interval in idiopathic ventricular fibrillation and long QT syndrome.
Heart. 2005 May 20; [Epub ahead of print]
PMID: 15908480 [PubMed - as supplied by publisher]

 

Shang YP, Xie XD, Wang XX, Chen JZ, Zhu JH, Tao QM, Zheng LR.

 

A novel splice mutation of HERG in a Chinese family with long QT syndrome.
J Zhejiang Univ Sci. 2005 Jul;6(7):626-30.
PMID: 15973763 [PubMed - in process]

 

Shimizu W, Aiba T, Antzelevitch C.

 

Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome.
Curr Pharm Des. 2005;11(12):1561-72. Review.
PMID: 15892662 [PubMed - indexed for MEDLINE]

 

Tester DJ, Kopplin LJ, Creighton W, Burke AP, Ackerman MJ.

 

Pathogenesis of unexplained drowning: new insights from a molecular autopsy.
Mayo Clin Proc. 2005 May;80(5):596-600.
PMID: 15887426 [PubMed - indexed for MEDLINE]

 

Wilson AJ, Quinn KV, Graves FM, Bitner-Glindzicz M, Tinker A.

 

Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1).
Cardiovasc Res. 2005 May 31; [Epub ahead of print]
PMID: 15935335 [PubMed - as supplied by

 

Shah RR, Hondeghem LM.

 

Refining detection of drug-induced proarrhythmia: QT interval and TRIaD.
Heart Rhythm. 2005 Jul;2(7):758-72.
PMID: 15992736 [PubMed - in process]

 

Skinner JR.

 

Is there a relation between SIDS and long QT syndrome?
Arch Dis Child. 2005 May;90(5):445-9. No abstract available.
PMID: 15851422 [PubMed - indexed for MEDLINE

 

Rossenbacker T, Schollen E, Kuiperi C, de Ravel TJ, Devriendt K, Matthijs G, Collen D, Heidbuchel H, Carmeliet P.

 

Unconventional intronic splice site mutation in SCN5A associates with cardiac sodium channelopathy.
J Med Genet. 2005 May;42(5):e29.
PMID: 15863661 [PubMed - in process]

 

Dilaveris PE.

 

Molecular predictors of drug-induced prolongation of the QT interval.
Curr Med Chem Cardiovasc Hematol Agents. 2005 Apr;3(2):105-18. Review.
PMID: 15853698 [PubMed - indexed for MEDLINE]

 

Kanters JK, Fanoe S, Larsen LA, Bloch Thomsen PE, Toft E, Christiansen M.

 

T wave morphology analysis distinguishes between KvLQT1 and HERG mutations in long QT syndrome.
Heart Rhythm. 2004 Sep;1(3):285-92.
PMID: 15851171 [PubMed - indexed for MEDLINE]

 

Thomas D, Wimmer AB, Karle CA, Licka M, Alter M, Khalil M, Ulmer HE, Kathofer S, Kiehn J, Katus HA, Schoels W, Koenen M, Zehelein J.

 

Dominant-negative I(Ks) suppression by KCNQ1-DeltaF339 potassium channels linked to Romano-Ward syndrome.
Cardiovasc Res. 2005 Jun 8; [Epub ahead of print]
PMID: 15950200 [PubMed - as supplied by publisher]

 

Tan BH, Valdivia CR, Rok BA, Ye B, Ruwaldt KM, Tester DJ, Ackerman MJ, Makielski JC.

 

Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants.
Heart Rhythm. 2005 Jul;2(7):741-7.
PMID: 15992732 [PubMed - in process]

 

Maekawa K, Saito Y, Ozawa S, Adachi-Akahane S, Kawamoto M, Komamura K, Shimizu W, Ueno K, Kamakura S, Kamatani N, Kitakaze M, Sawada J.

 

Genetic Polymorphisms and Haplotypes of the Human Cardiac Sodium Channel alpha Subunit Gene (SCN5A) in Japanese and their Association with Arrhythmia.
Ann Hum Genet. 2005 Jul;69(Pt 4):413-28.
PMID: 15996170 [PubMed - in process]

 

Guo L, Guthrie H.

 

Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation.
J Pharmacol Toxicol Methods. 2005 Jun 1; [Epub ahead of print]
PMID: 15936217 [PubMed - as supplied by publisher]

 

Paulussen AD, Raes A, Jongbloed RJ, Gilissen RA, Wilde AA, Snyders DJ, Smeets HJ, Aerssens J.

 

HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Cardiovasc Res. 2005 Jun 13; [Epub ahead of print]
PMID: 15958262 [PubMed - as supplied by publisher

 

Jonker DM, Kenna LA, Leishman D, Wallis R, Milligan PA, Jonsson EN.

 

A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data.
Clin Pharmacol Ther. 2005 Jun;77(6):572-82.
PMID: 15961988 [PubMed - in process]

 

Dorn A, Hermann F, Ebneth A, Bothmann H, Trube G, Christensen K, Apfel C.

 

Evaluation of a high-throughput fluorescence assay method for HERG potassium channel inhibition.
J Biomol Screen. 2005 Jun;10(4):339-47.
PMID: 15964935 [PubMed - in process]

 

Wible BA, Hawryluk P, Ficker E, Kuryshev YA, Kirsch G, Brown AM.

 

HERG-Lite(R): A novel comprehensive high-throughput screen for drug-induced hERG risk.
J Pharmacol Toxicol Methods. 2005 Jun 8; [Epub ahead of print]
PMID: 15950494 [PubMed - as supplied by publisher]

 

Yao JA, Du X, Lu D, Baker RL, Daharsh E, Atterson P.

 

Estimation of potency of HERG channel blockers: Impact of voltage protocol and temperature.
J Pharmacol Toxicol Methods. 2005 Jun 1; [Epub ahead of print]
PMID: 15936218 [PubMed - as supplied by publisher]

 

Ducroq J, Printemps R, Le Grand M.

 

Additive effects of ziprasidone and d,l-sotalol on the action potential in rabbit Purkinje fibres and on the hERG potassium current.
J Pharmacol Toxicol Methods. 2005 May 25; [Epub ahead of print]
PMID: 15922632 [PubMed - as supplied by publisher]

 

Tobita M, Nishikawa T, Nagashima R.

 

A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Bioorg Med Chem Lett. 2005 Jun 2;15(11):2886-90.
PMID: 15911273 [PubMed - in process]

 

Miranda P, Giraldez T, de la Pena P, Manso DG, Alonso-Ron C, Gomez-Varela D, Dominguez P, Barros F.

 

Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells.
J Physiol. 2005 May 19; [Epub ahead of print]
PMID: 15905217 [PubMed - as supplied by publisher]

 

Persson F, Carlsson L, Duker G, Jacobson I.

 

Blocking characteristics of hERG, hNav1.5, and hKvLQT1/hminK after administration of the novel anti-arrhythmic compound AZD7009.
J Cardiovasc Electrophysiol. 2005 Mar;16(3):329-41.
PMID: 15817095 [PubMed - in process]

 

Schneider J, Hauser R, Andreas JO, Linz K, Jahnel U.

 

Differential effects of human ether-a-go-go-related gene (HERG) blocking agents on QT duration variability in conscious dogs.
Eur J Pharmacol. 2005 Apr 4;512(1):53-60.
PMID: 15814090 [PubMed - in process]

 

Chen SZ, Jiang M, Zhen YS.

 

HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin.
Cancer Chemother Pharmacol. 2005 Aug;56(2):212-20. Epub 2005 Apr 6.
PMID: 15812674 [PubMed - in process]

 

Vaz RJ, Li Y, Rampe D.

 

Human Ether-a-go-go Related Gene (HERG): A Chemist's Perspective.
Prog Med Chem. 2005;43:1-18. No abstract available.
PMID: 15850821 [PubMed - in process]

 

Lin J, Guo J, Gang H, Wojciechowski P, Wigle JT, Zhang S.

 

Intracellular K+ is required for the inactivation-induced high affinity binding of cisapride to HERG channels.
Mol Pharmacol. 2005 Jun 20; [Epub ahead of print]
PMID: 15967876 [PubMed - as supplied by publisher]

 

Fernandez D, Ghanta A, Kinard K, Sanguinetti M.

 

Molecular mapping of a binding site for Cd2+- induced modification of hERG channel activation.
J Physiol. 2005 Jun 23; [Epub ahead of print]
PMID: 15975984 [PubMed - as supplied by publisher]

 

Zhou J, Augelli-Szafran CE, Bradley JA, Chen X, Koci BJ, Volberg WA, Sun Z, Cordes JS.

 

Novel Potent hERG Potassium Channel Enhancers And Their In Vitro Antiarrhythmic Activity.
Mol Pharmacol. 2005 Jun 23; [Epub ahead of print]
PMID: 15976038 [PubMed - as supplied by publisher]

 

Cianchetta G, Li Y, Kang J, Rampe D, Fravolini A, Cruciani G, Vaz RJ.

 

Predictive models for hERG potassium channel blockers.
Bioorg Med Chem Lett. 2005 Jun 21; [Epub ahead of print]
PMID: 15978804 [PubMed - as supplied by publisher]

 

Matasi JJ, Caldwell JP, Zhang H, Fawzi A, Higgins GA, Cohen-Williams ME, Varty GB, Tulshian DB.

 

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A(2A) antagonists: The successful reduction of hERG activity. Part 2.
Bioorg Med Chem Lett. 2005 Jun 24; [Epub ahead of print]
PMID: 15982882 [PubMed - as supplied by publisher]

 

Siebrands CC, Schmitt N, Friederich P.

 

Local Anesthetic Interaction with Human Ether-a-go-go-related Gene (HERG) Channels: Role of Aromatic Amino Acids Y652 and F656.
Anesthesiology. 2005 Jul;103(1):102-112.
PMID: 15983462 [PubMed - as supplied by publisher]

 

Guizy M, Arias C, David M, Gonzalez T, Valenzuela C.

 

{omega}-3 and {omega}-6 Polyunsaturated Fatty Acids block HERG Channels.
Am J Physiol Cell Physiol. 2005 Jun 29; [Epub ahead of print]
PMID: 15987770 [PubMed - as supplied by publisher]

Miscellaneaous

 

Lerecouvrex M, Ait Said M, Paziaud O, Perrier E, Carlioz R, Lavergne T, Guize L, Le Heuzey JY.

 

Automobile driving and implantable defibrillators
Arch Mal Coeur Vaiss. 2005 Apr;98(4):288-93. French.
PMID: 15881843 [PubMed - indexed for MEDLINE]

 

Tester DJ, Ackerman MJ.

 

Sudden infant death syndrome: How significant are the cardiac channelopathies?
Cardiovasc Res. 2005 May 20; [Epub ahead of print]
PMID: 15913580 [PubMed - as supplied by publisher]

 

Corrado D, Pelliccia A, Bjornstad HH, Thiene G.

 

Cardiovascular pre-participation screening of young competitive athletes for prevention of sudden death: proposal for a common European protocol; reply.
Eur Heart J. 2005 Jun 17; [Epub ahead of print]
PMID: 15964856 [PubMed - as supplied by publisher]

 

Lawrence CL, Pollard CE, Hammond TG, Valentin JP.

 

Nonclinical proarrhythmia models: Predicting Torsades de Pointes.
J Pharmacol Toxicol Methods. 2005 Jun 20; [Epub ahead of print]
PMID: 15975832 [PubMed - as supplied by publisher]

 

Mok NS, Chan NY.

 

Supraventricular Tachycardia with a Baseline ECG Pattern of Brugada Syndrome.
Pacing Clin Electrophysiol. 2005 Jun;28(6):602-3.
PMID: 15955199 [PubMed - in process]

 

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